Treating Tear Troughs & Crepey Under-Eye Skin: PRP Therapy Layered with Jalupro Classic

The under-eye area is one of the first regions of the face where the visible signs of ageing become noticeable. Many patients describe hollow tear troughs, persistent dark circles, and increasingly crepey or thin skin beneath the eyes — concerns that can be difficult to address through skincare products alone. It is entirely understandable that patients in London and beyond turn to online research when exploring aesthetic treatment options for this delicate area.

This article explores PRP therapy layered with Jalupro Classic for tear trough and under-eye skin concerns — a combined approach that has attracted growing interest within medical aesthetic practice. We will cover how each treatment works, why they are sometimes used together, what patients might realistically expect, who may benefit from a professional consultation, and important considerations around suitability, limitations, and aftercare.

As always, individual treatment suitability should only be determined following a thorough assessment with a qualified aesthetic practitioner.

PRP therapy layered with Jalupro Classic is a combined aesthetic approach used to address tear troughs and crepey under-eye skin. PRP (Platelet-Rich Plasma) uses growth factors from the patient's own blood to support tissue regeneration, while Jalupro Classic delivers amino acids to help restore skin quality. Together, they may support skin hydration, texture, and structural improvement in a clinically responsible and gradual manner.

The tear trough refers to the groove or hollow that forms between the lower eyelid and the cheek. For some individuals, this area appears sunken, shadowed, or darkened — creating an impression of tiredness or ageing that does not necessarily reflect how a person feels.

As the face ages, several structural changes occur beneath the skin. Volume is gradually lost from the mid-face fat compartments, and the supporting ligaments and tissues become lax over time. This can cause the tear trough to deepen and become more pronounced. Meanwhile, the delicate skin in the under-eye area — which is significantly thinner than skin elsewhere on the face — loses collagen and elastin over time, resulting in what is commonly described as crepey skin. Fine lines may appear, the skin may appear translucent, and in some cases, underlying vasculature becomes more visible.

These changes are a natural part of the ageing process and can be influenced by genetics, lifestyle factors such as sun exposure and sleep quality, and general skin health. Understanding the structural causes of under-eye concerns is an important first step in exploring what treatment approaches may be appropriate for a given individual.

Platelet-Rich Plasma (PRP) therapy is a treatment that uses a small sample of the patient's own blood. This sample is processed using a centrifuge — a device that separates the blood into its different components. The resulting plasma, which contains a concentrated level of platelets and growth factors, is then prepared for therapeutic use.

PRP has been used in various medical specialities for a number of years, and within aesthetic medicine it has been applied to address skin quality concerns, stimulate collagen production, and support tissue regeneration. When administered in the under-eye area, the growth factors within PRP are understood to interact with the skin's natural cellular mechanisms, encouraging the production of new collagen and supporting the overall health of the skin's structural framework.

PRP is not a filler and does not add volume in the same way as hyaluronic acid-based dermal fillers. Rather, it works over time by stimulating the skin's own regenerative processes. Because it uses the patient's own biological material, PRP is generally considered to carry a relatively low risk of allergic reaction, though risks and suitability must still be assessed on an individual basis by a qualified practitioner.

Jalupro Classic is a biorevitalisation injectable treatment containing a combination of amino acids and hyaluronic acid. Amino acids are the fundamental building blocks of proteins — including collagen and elastin — which are essential components of healthy, resilient skin.

The formulation is designed to deliver these active ingredients directly into the dermis, supporting the skin's natural capacity to regenerate and maintain its structural integrity. Jalupro Classic is not a dermal filler in the traditional sense; it does not aim to restore volume but rather to improve skin quality, hydration, and texture from within.

In the context of under-eye treatment, Jalupro Classic may be considered for its potential to support skin firmness, reduce the appearance of fine lines associated with skin laxity, and address the crepey skin texture that can develop in this delicate region. The hyaluronic acid component contributes to hydration, while the amino acid blend supports the conditions necessary for collagen synthesis.

As with all aesthetic treatments, results vary between individuals and are not guaranteed. Suitability must be assessed by a qualified practitioner prior to treatment.

The concept of layering PRP therapy with Jalupro Classic stems from the complementary nature of their mechanisms of action. Both treatments aim to work with the skin's own biology rather than introducing external volumising agents, making the combination of particular interest for the delicate under-eye area, where over-correction or inappropriate treatment carries meaningful risks.

PRP contributes growth factors that signal the skin's fibroblasts — the cells responsible for producing collagen and elastin — to increase their activity. Jalupro Classic, in turn, provides the amino acid substrates that these fibroblasts need to synthesise new structural proteins effectively.

Together, the two treatments may offer a more comprehensive approach to improving skin quality than either intervention alone. The combination targets both the cellular signalling environment (through PRP) and the nutritional building blocks required for skin regeneration (through Jalupro Classic's amino acid profile).

It is important to note that this is an evolving area of aesthetic medicine. While clinical observations and emerging evidence are encouraging, treatment outcomes vary between individuals. A thorough consultation with a qualified aesthetic professional is essential to determine whether this approach may be appropriate for a given patient's anatomy, skin condition, and treatment goals.

The skin beneath the eyes is structurally distinct from skin elsewhere on the face. It is notably thinner — sometimes as little as half a millimetre in depth — and contains fewer sebaceous (oil) glands, making it more susceptible to dehydration and environmental damage.

From the mid-twenties onwards, the skin's production of collagen begins to decline gradually. Collagen is the primary structural protein that gives skin its firmness and resilience. Alongside collagen, elastin — the protein responsible for the skin's ability to snap back into shape — also degrades over time. Without adequate collagen and elastin, the skin becomes thinner, less elastic, and more prone to developing the fine crepey texture that many patients find concerning in the under-eye region.

The tear trough hollow is further deepened by the loss of subcutaneous fat and the downward shift of facial fat compartments under the influence of gravity and reduced ligamentous support. This structural loss creates shadowing that can contribute to the appearance of dark circles, even in the absence of pigmentation changes. For readers comparing causes of under-eye darkness in more detail, this companion guide on dark circles and vascular shadowing may be helpful.

PRP and Jalupro Classic both target aspects of this biological process — PRP by stimulating fibroblast activity and growth factor signalling, and Jalupro Classic by supplying amino acids that support collagen synthesis. Neither treatment reverses the ageing process, but they may support the skin's capacity to maintain or modestly improve its structural quality over time.

A professional aesthetic consultation may be a helpful next step for individuals who:

• Notice hollowing or shadowing beneath the eyes that has become more pronounced over time
• Experience skin that feels or appears thinner, dryer, or more crepey in the under-eye area
• Have concerns about fine lines or wrinkles developing beneath the eyes
• Have explored topical skincare solutions without achieving their desired skin quality improvements
• Are curious about non-surgical approaches to supporting the appearance of the under-eye area
• Would like to understand what treatment options may or may not be appropriate for their specific anatomy and skin type

It is important to emphasise that attending a consultation does not commit a patient to any treatment. A qualified practitioner will take a thorough medical history, assess the anatomy of the area in question, and discuss the full range of options — including whether intervention is appropriate at all.

Patients with certain medical conditions, those taking specific medications, or those who are pregnant or breastfeeding may not be suitable candidates for PRP or injectable treatments. This is precisely why individual assessment is essential before any treatment plan is recommended.

As with all aesthetic treatments, it is important that patients approach PRP therapy layered with Jalupro Classic with informed and realistic expectations.

Potential benefits that may be observed over a course of treatment include:

• Gradual improvement in under-eye skin texture and hydration
• Reduction in the appearance of fine crepey lines associated with skin laxity
• Modest softening of the tear trough shadow in appropriate candidates
• Improvement in overall skin quality in the treated area

Important limitations and considerations include:

• Results are gradual and typically require multiple treatment sessions — often three or more — before meaningful change is visible
• Outcomes vary considerably between individuals and are influenced by factors including age, skin condition, genetics, lifestyle, and the degree of structural change present
• Neither PRP nor Jalupro Classic is designed to replace significant volume loss in the tear trough; patients with notable hollowing may require a different or additional approach
• Results are not permanent; maintenance treatments are likely to be necessary to sustain any improvement achieved
• Not all patients will respond to treatment, and in some cases, results may be subtle

An honest and thorough discussion of expectations forms an essential part of any responsible pre-treatment consultation.

Both PRP therapy and Jalupro Classic involve injections into the skin using fine needles. Topical anaesthetic cream is typically applied prior to treatment to minimise discomfort, and practitioners will take care to explain what to expect at each stage.

Following treatment in the under-eye area, patients should expect some degree of:

• Mild redness and swelling in the treated area, which typically resolves within a few days
• Possible bruising, particularly in the thin-skinned under-eye region, which may take up to one to two weeks to fully resolve
• Temporary tenderness at injection sites

The under-eye area is particularly prone to bruising due to the density of small blood vessels in this region. Patients should factor this into their scheduling decisions if they have social or professional commitments in the days following treatment.

Most patients are able to return to their normal daily activities shortly after treatment, though strenuous exercise, alcohol, and excessive heat (such as saunas or hot baths) are typically advised against for a short period post-treatment. Specific aftercare guidance will be provided by the treating practitioner.

Good aftercare supports the healing process and may help optimise the outcomes of treatment. General guidance following PRP and Jalupro Classic treatment in the under-eye area may include:

• Avoiding touching or applying pressure to the treated area in the immediate hours following treatment
• Using a gentle, fragrance-free cleanser and avoiding active skincare ingredients such as retinoids or acids on the treated area for a recommended period
• Applying a broad-spectrum SPF daily — sun protection is essential year-round, particularly in the delicate under-eye area, where UV exposure accelerates collagen breakdown
• Staying well hydrated to support the skin's recovery and overall health
• Avoiding alcohol for at least 24 hours following treatment, as this can increase bruising and swelling
• Sleeping with the head slightly elevated in the first night or two following treatment to help minimise swelling
• Attending follow-up appointments as advised by the practitioner to monitor progress and determine whether additional sessions are appropriate

Patients should follow the specific aftercare instructions provided by their treating practitioner, as guidance may vary depending on the individual treatment administered.

Patients researching under-eye concerns will encounter a range of treatment options, from topical eye creams to hyaluronic acid-based under-eye treatment options and energy-based skin treatments. Understanding how PRP with Jalupro Classic compares to other approaches may help patients frame their consultation questions more effectively.

Hyaluronic acid dermal fillers placed in the tear trough area can provide more immediate and pronounced volumising results for patients with significant hollowing. However, this area carries specific anatomical risks and requires precise placement by a highly experienced practitioner.

PRP and Jalupro Classic, by contrast, focus on improving skin quality and supporting the skin's own biology rather than adding volume. For patients whose primary concern is skin texture, crepiness, and mild shadowing rather than deep structural hollowing, this approach may be a clinically appropriate starting point.

Some patients may benefit from a combination of approaches over time. This is a conversation best had during a one-to-one consultation, where the practitioner can assess anatomy, skin quality, and treatment goals together.

• Tear troughs and crepey under-eye skin are common concerns associated with the natural ageing process and changes in facial structure, volume, and skin quality over time.
• PRP therapy layered with Jalupro Classic is a combined biorevitalisation approach that aims to support skin regeneration, hydration, and texture improvement in the under-eye area using the patient's own growth factors and amino acid supplementation.
• Results are gradual, variable, and not guaranteed — multiple treatment sessions are typically required, and outcomes depend on individual factors including anatomy, skin condition, age, and lifestyle.
• This approach is not suitable for everyone — individual assessment by a qualified aesthetic practitioner is essential before any treatment plan is discussed or undertaken.
• Realistic expectations and informed consent are fundamental to a responsible aesthetic treatment experience.
• Aftercare, sun protection, and healthy lifestyle habits all play an important role in supporting skin health alongside any aesthetic treatment.

How many sessions of PRP and Jalupro Classic are typically needed for under-eye concerns?

The number of sessions required varies between individuals and depends on the degree of concern, skin condition, and how the skin responds to treatment. Many practitioners suggest an initial course of three sessions, spaced approximately three to four weeks apart, as a starting point. Some patients may require additional sessions or periodic maintenance treatments to sustain results. This should be discussed and planned during a professional consultation, as there is no universal protocol that applies to every patient.

Is PRP therapy combined with Jalupro Classic suitable for all skin types and ages?

No aesthetic treatment is universally suitable for all patients. PRP and Jalupro Classic are generally considered to be broadly tolerable, as they work with the skin's own biology rather than introducing synthetic foreign materials. However, suitability depends on individual health history, medications, and the specific nature of the under-eye concerns being addressed. Certain medical conditions or medications may contraindicate treatment. Age, skin condition, and anatomy will also influence whether this approach is appropriate. A thorough consultation with a qualified practitioner is the only way to determine individual suitability.

Are there risks associated with treating the tear trough area?

Yes. The tear trough and under-eye region is anatomically complex and requires careful assessment and precise technique. As with any injectable treatment, there are risks including bruising, swelling, infection, and in rare cases more serious complications. The thin skin in this area can make bruising more visible and prolonged. Patients should ensure they seek treatment from a suitably qualified and experienced medical professional, and should discuss all potential risks in full during a pre-treatment consultation.

How long do results from PRP and Jalupro Classic last in the under-eye area?

Results are not permanent. The duration of improvement varies depending on individual factors including skin condition, age, lifestyle, and how many treatment sessions have been completed. Some patients may notice sustained improvement for six to twelve months, while others may require maintenance treatments sooner. Ongoing sun protection and a healthy skincare routine can help support the longevity of results. Maintenance treatment frequency should be discussed with the treating practitioner based on individual response and goals.

Can PRP and Jalupro Classic replace tear trough dermal fillers?

PRP and Jalupro Classic serve a different primary purpose to tear trough dermal fillers. Fillers aim to restore volume and directly address structural hollowing, while PRP and Jalupro Classic focus on improving skin quality, hydration, and texture. For patients with significant volume loss in the tear trough area, fillers may be a more appropriate primary intervention. For those whose main concern is skin crepiness and quality rather than hollowing, PRP and Jalupro Classic may be a suitable option. Some patients may benefit from a combined approach over time. Individual assessment is essential to determine which approach — or combination of approaches — is most appropriate.

What should I look for when choosing a practitioner for under-eye aesthetic treatment?

Patients should seek treatment from a qualified and regulated healthcare professional with specific training and demonstrable experience in treating the periorbital (eye) area. The under-eye region is anatomically sensitive, and treatment here carries particular risks if not performed by a suitably experienced practitioner. Look for practitioners who are registered with a recognised professional body, who conduct thorough pre-treatment consultations, provide written information about risks and aftercare, and who operate within regulated clinical environments. The Pantaleo aesthetic consultation process is designed to support informed patient decision-making at every stage.

The tear trough and under-eye area present some of the most nuanced challenges in aesthetic medicine. The combination of structural volume loss, skin thinning, and reduced collagen production creates concerns — including deepened hollows, shadowing, and crepey skin texture — that are difficult to address through topical skincare alone.

PRP therapy layered with Jalupro Classic represents an increasingly discussed approach within medical aesthetics, offering a biologically supportive strategy that works with the skin's own regenerative capacity. By combining the growth factor stimulation of PRP with the amino acid nourishment of Jalupro Classic, this layered approach aims to gradually improve skin quality, hydration, and texture in a clinically considered manner.

However, this treatment is not appropriate for everyone, results vary between individuals, and outcomes are never guaranteed. The under-eye area is a complex anatomical zone that demands careful assessment and skilled clinical technique.

Informed patients make better decisions. Understanding the science, the realistic expectations, and the importance of selecting a qualified and experienced practitioner are all essential parts of that process.

Treatment suitability, risks, and expected outcomes should always be assessed individually during a professional consultation.

If you are considering aesthetic treatment for tear trough or under-eye skin concerns, we encourage you to seek personalised advice from a qualified medical professional who can assess your unique anatomy, skin condition, and treatment goals before any decisions are made.