Skin & Rejuvenation
How the Deep Fat Pads Shift with Age: An Anatomical Overview for Patients

Many people notice that as they grow older, their face begins to look somewhat different — not simply because the skin has changed, but because the overall shape and contour of the face appears to have altered. Common observations include a hollowing beneath the eyes, a flattening of the cheeks, or a deepening of the lines that run from the nose to the corners of the mouth. These changes are often puzzling, particularly when they seem to happen gradually and yet become quite pronounced over time.
Introduction
Many people notice that as they grow older, their face begins to look somewhat different — not simply because the skin has changed, but because the overall shape and contour of the face appears to have altered. Common observations include a hollowing beneath the eyes, a flattening of the cheeks, or a deepening of the lines that run from the nose to the corners of the mouth. These changes are often puzzling, particularly when they seem to happen gradually and yet become quite pronounced over time.
What many patients may not realise is that a significant contributor to these changes lies beneath the skin itself, within the deep facial fat pads — discrete compartments of fat that sit beneath the superficial tissue layers of the face. As these fat pads change in volume and position with age, the surface appearance of the face shifts accordingly.
This article provides an educational anatomical overview of the deep facial fat pads, how they change over time, why these changes matter, and when a professional aesthetic consultation may be a useful next step. Understanding the anatomy of facial ageing can help patients make more informed decisions about their skincare and any aesthetic treatments they may be considering.
What Are the Deep Facial Fat Pads and How Do They Change with Age?
The deep facial fat pads are discrete anatomical compartments of fat located beneath the superficial muscles and tissue of the face. With age, these fat pads lose volume, descend, and become redistributed. This process contributes to hollowing under the eyes, flattening of the mid-face, and deepening of facial folds — changes that are a natural part of the facial ageing process.
Understanding Facial Fat: It Is Not One Continuous Layer
When most people think of facial fat, they imagine a single, uniform layer beneath the skin. In reality, the fat of the face is arranged in a series of distinct compartments — both superficial and deep — separated by fibrous walls known as septa. This architectural arrangement has been well documented in anatomical research and is central to understanding why faces age the way they do.
The deep facial fat pads sit beneath the superficial muscular aponeurotic system (SMAS) — the layer of muscle and connective tissue that surgeons and aesthetic practitioners reference when assessing facial structure. Key deep fat compartments include the deep medial cheek fat, the sub-orbicularis oculi fat (SOOF), the deep temporal fat pad, and the buccal fat pad, among others.
Each of these compartments plays a role in supporting the overlying tissue layers, contributing to the contours that characterise a youthful facial appearance. Because they are situated deep within the face, their changes have a significant structural impact — often more so than changes occurring in the superficial fat layers or the skin itself.
Understanding that the face is composed of these distinct anatomical compartments helps explain why facial ageing is not simply a matter of skin laxity, but a complex, three-dimensional process involving bone, fat, muscle, and soft tissue simultaneously.
How the Deep Fat Pads Change Over Time
Facial ageing is a multifactorial process, and the deep fat pads are subject to a range of changes as the years pass. Research in anatomical and aesthetic medicine has identified several consistent patterns:
Volume Deflation The deep fat compartments tend to reduce in overall volume with age. This deflation is a natural consequence of metabolic and hormonal changes, and it means that the structural support these pads previously provided to overlying tissue begins to diminish. The result is often a flattening or hollowing of areas that previously appeared full and rounded.
Positional Descent In addition to losing volume, the deep fat pads can descend over time due to the effects of gravity and the progressive weakening of the retaining ligaments that hold facial structures in position. This descent can cause previously supported areas — such as the mid-cheek — to appear lower, contributing to the appearance of jowling and a less defined jawline.
Uneven Redistribution The fat pads do not all change at the same rate. Some compartments deflate more rapidly than others, while certain areas — such as the jowl region — may actually accumulate fat as the face ages. This uneven redistribution creates an imbalance in facial volume that contributes to the characteristic contour changes associated with ageing.
These processes are gradual, typically beginning in the mid-thirties and becoming more pronounced through the forties, fifties, and beyond. However, the rate and pattern of change varies considerably between individuals.
The Science Behind Facial Volume Loss
To understand why the deep fat pads change, it is helpful to consider the broader biological processes involved in facial ageing.
Collagen and Structural Support Collagen is the primary structural protein in the skin and connective tissues. From around the mid-twenties, the body's collagen production begins to slow, and the quality of existing collagen fibres gradually declines. This affects not only the skin's surface — contributing to fine lines and reduced elasticity — but also the structural scaffolding that supports facial fat compartments. As the retaining ligaments weaken, the fat pads they anchor become less stable.
Hormonal Influences Hormonal changes — particularly the decline in oestrogen during the perimenopausal and postmenopausal years — can accelerate the loss of facial fat and collagen. This helps explain why many women notice more pronounced facial changes during this period of life.
Bone Remodelling The skeleton continues to change throughout adulthood. The facial bones — including the orbital rim, the maxilla, and the mandible — undergo remodelling with age, reducing in volume in key areas. As the bony scaffold of the face diminishes, the soft tissues it previously supported — including the deep fat pads — lose their foundation, contributing further to descent and volume loss.
Cellular Metabolism Within the fat compartments themselves, the metabolic activity of fat cells (adipocytes) changes with age. Fat cells in certain compartments may undergo atrophy (shrinkage), whilst those in other areas remain stable or expand. These differential changes across compartments are a key driver of the uneven volume distribution seen in older faces.
Understanding these science-based mechanisms can help patients appreciate that facial ageing is a structural and biological process — not simply a cosmetic concern — and that addressing it thoughtfully requires an understanding of anatomy.
The Mid-Face: A Key Area of Age-Related Change
The mid-face — the region encompassing the cheeks, the area beneath the eyes, and the upper portion of the nasolabial folds — is one of the areas most visibly affected by changes in the deep fat pads. This is because the deep medial cheek fat pad and the sub-orbicularis oculi fat (SOOF) are central contributors to the youthful convexity of the cheek.
In youth, the cheek typically presents as a gently rounded, full contour, with a smooth transition between the lower eyelid and the cheek. This appearance is partly attributable to the volume and position of the deep fat pads in this region.
As these pads deflate and descend with age, several visible changes may occur:
Tear trough deepening: The junction between the lower eyelid and the cheek becomes more pronounced, creating a hollowed or shadowed appearance beneath the eyes. Our guide on whether you may be a candidate for under-eye injectables explores assessment criteria in detail. Flattening of the mid-cheek: The previously rounded cheek contour appears flatter or more concave. Nasolabial fold deepening: As the cheek descends, the skin and soft tissue of the lower face buckle slightly, deepening the folds that run from the nose to the corners of the mouth. Loss of ogee curve: The gentle S-shaped contour that characterises youthful facial aesthetics becomes less defined.
These changes are a normal part of the ageing process and do not indicate any medical concern. However, for patients who find them aesthetically significant, understanding their anatomical basis is an important first step in exploring any treatment options. For those interested in how mid-face changes cascade into lower facial expression, a dedicated guide explores this topic in detail alongside what a practitioner may be able to achieve.
The Buccal Fat Pad: A Special Consideration
The buccal fat pad occupies a unique position in discussions of facial ageing. Located in the lower cheek region, it is one of the larger fat compartments of the face and plays a complex role in how the lower face ages.
In younger individuals, the buccal fat pad contributes to the fullness of the lower cheek. With age, however, the buccal fat may descend anteriorly and inferiorly, contributing to jowl formation and a less defined jawline. In some individuals, it may remain relatively stable in volume while the surrounding structures change, creating an appearance of disproportionate lower facial fullness.
This variability between individuals highlights an important principle: no two faces age in exactly the same way. Individual differences in genetics, lifestyle, body composition, sun exposure, and hormonal status all influence the rate and pattern of deep fat pad change. This is one of the reasons why a thorough individual assessment is so important before any aesthetic intervention is considered.
How Bone, Muscle, and Fat Interact in Facial Ageing
It would be an oversimplification to consider the deep fat pads in isolation. Facial ageing is a dynamic process involving the simultaneous change of multiple anatomical layers, and these layers interact with one another in complex ways.
Bone loss reduces the support provided to overlying fat and soft tissue, accelerating descent.
Muscle changes — including both hypertrophy (overactivity) in certain muscles and atrophy (weakening) in others — alter the way that surface movements interact with underlying fat compartments.
Skin laxity resulting from collagen and elastin degradation means that the skin envelope becomes less able to compensate for the volume loss occurring in deeper layers.
Ligament laxity reduces the anchoring that holds fat compartments in position, contributing to descent.
This interplay explains why comprehensive facial assessment by an experienced aesthetic practitioner considers the face as a whole, rather than focusing on isolated features. Addressing volume loss in one area without considering surrounding structures can sometimes produce results that appear unnatural or imbalanced.
Understanding this complexity also helps set realistic expectations: achieving natural-looking facial rejuvenation requires a nuanced, anatomically informed approach — and cannot be reduced to a single product or treatment.
Who May Benefit from a Professional Aesthetic Consultation?
Whilst the changes described in this article are a normal part of ageing, some patients may reach a point where they wish to discuss their options with a qualified aesthetic practitioner. A professional consultation does not commit anyone to any treatment — it is simply an opportunity to receive accurate, personalised information.
Situations where a consultation may be helpful include:
Noticing significant volume loss in the cheeks or mid-face that is causing concern Increased hollowing beneath the eyes that feels disproportionate or is affecting confidence Deepening nasolabial folds or marionette lines that are prompting questions about options A general sense that the face looks "tired" even when well-rested, often attributable to structural volume changes Curiosity about what treatment options exist and whether any are appropriate for an individual's anatomy and concerns Questions about non-surgical approaches to facial rejuvenation and how they work anatomically
A practitioner registered with the General Medical Council (GMC), General Dental Council (GDC), or Nursing and Midwifery Council (NMC), operating within a CQC-regulated clinical environment, will take a thorough medical history, assess facial anatomy holistically, discuss realistic outcomes, and advise on the most appropriate approach — which may or may not involve aesthetic treatment. Those considering a first consultation can book a consultation with our London team.
It is important to emphasise that no treatment is universally suitable, and professional assessment is always the appropriate starting point.
Treatment Approaches That Address Deep Fat Pad Changes
For educational purposes, it is worth briefly outlining the types of aesthetic interventions that practitioners may discuss in the context of deep fat pad volume loss. This is not an endorsement of any specific treatment, and suitability depends entirely on individual assessment.
Dermal Fillers Hyaluronic acid-based dermal fillers are commonly used to restore volume in areas affected by deep fat pad deflation, such as the cheeks, temples, and under-eye region. When placed by an experienced practitioner with detailed anatomical knowledge, fillers can help restore structural support to overlying tissues. However, they carry risks and are not appropriate for everyone. In England, the Health and Care Act 2022 requires that aesthetic injectable treatments, including dermal fillers, are administered only by registered healthcare professionals. Patients exploring under-eye treatment for tear trough hollowing will find the approach discussed in detail during consultation. These treatments are not appropriate for those under 18 years of age.
Polynucleotides (PDRN/PN) Skin booster treatments and polynucleotide therapies work by stimulating tissue regeneration and improving skin quality. Whilst they do not directly replace lost fat pad volume, they may complement structural treatments by improving skin tone and hydration in areas affected by ageing.
Surgical Options For patients with more advanced signs of facial ageing, surgical interventions such as fat transfer or facelift procedures may be discussed by surgeons. These are beyond the scope of non-surgical aesthetic clinics and require separate specialist assessment.
Any discussion of treatment options should always take place within the context of a thorough consultation, where the practitioner can assess anatomy, review medical history, discuss risks and benefits, and provide individually tailored guidance.
Realistic Expectations, Benefits, and Limitations
Understanding what aesthetic treatments can and cannot achieve is an important part of the decision-making process.
Potential Benefits When anatomically appropriate and carried out by a suitably qualified practitioner, treatments addressing deep fat pad volume loss may help to:
Restore a degree of structural support to areas of deflation Improve the transition between facial zones (such as the lower eyelid and cheek) Contribute to a more rested or refreshed facial appearance Soften the appearance of deepened folds associated with volume loss
Important Limitations Non-surgical treatments cannot halt the underlying ageing process Results are temporary and require maintenance Outcomes vary considerably between individuals based on anatomy, skin quality, and the extent of volume loss Not all patients are suitable candidates for volumising treatments Overfilling can produce unnatural results — experienced, conservative practitioners prioritise anatomical balance Some changes associated with ageing — including bone loss and skin laxity — may not be fully addressable through non-surgical means alone
Individual Variation Facial anatomy is highly individual. The degree of deep fat pad volume loss, the pattern of descent, and the response to treatment all vary between patients. This is why personalised assessment is essential before any treatment decision is made.
Supporting Skin Health: General Aftercare and Lifestyle Guidance
Regardless of whether aesthetic treatment is pursued, there are evidence-informed lifestyle and skincare measures that support overall facial skin health and may help to slow some aspects of the ageing process.
Daily Sun Protection Ultraviolet (UV) radiation is one of the most significant accelerators of skin ageing. Applying a broad-spectrum SPF 30 or higher sunscreen daily — including during winter months and on overcast days — is one of the most effective skin health habits. UV exposure degrades collagen and elastin, worsening the soft tissue laxity that compounds volume loss.
Skin Hydration and Barrier Support Using a well-formulated moisturiser appropriate for your skin type helps to maintain the skin barrier, reducing transepidermal water loss and supporting overall skin quality. Hyaluronic acid-based serums and ceramide-containing moisturisers are commonly recommended.
Evidence-Based Skincare Ingredients Retinoids (vitamin A derivatives) have the most robust evidence base for supporting collagen synthesis and improving skin texture with consistent use. Vitamin C serums can support collagen production and offer antioxidant protection. Any active skincare ingredients should be introduced gradually and in consultation with a skincare professional if there is uncertainty about suitability.
Nutrition and Hydration A diet rich in antioxidants, healthy fats, and adequate protein supports skin health from within. Staying well hydrated contributes to skin plumpness and overall function. Minimising alcohol intake and avoiding smoking — both of which accelerate collagen degradation — is also beneficial.
Sleep and Stress Management Adequate sleep supports cellular repair processes, including those relevant to skin. Chronic stress elevates cortisol levels, which can accelerate collagen breakdown. Stress management strategies may therefore have indirect benefits for skin health.
These measures are supportive of overall health and skin quality, but they do not replace the structural changes that occur within the deep fat pad compartments — they complement them.
Key Points to Remember
The deep facial fat pads are distinct anatomical compartments that play a central role in facial structure and youthful contour. With age, these fat pads deflate, descend, and redistribute unevenly, contributing to volume loss, hollowing, and deepening of facial folds. Facial ageing involves multiple layers simultaneously — including bone, fat, muscle, and skin — and cannot be attributed to any single factor. The rate and pattern of change varies considerably between individuals, which is why personalised assessment is always the appropriate first step. Aesthetic treatments can address some aspects of deep fat pad volume loss, but they carry risks, have limitations, and are not suitable for everyone. Daily sun protection, good skincare habits, and healthy lifestyle choices support overall skin health regardless of whether any aesthetic treatment is pursued.
Frequently Asked Questions
At what age do the deep facial fat pads typically begin to change?
The deep facial fat pads begin to show changes gradually from around the mid-thirties, though this varies considerably between individuals. Factors including genetics, hormonal status, lifestyle, sun exposure, and overall health all influence the rate at which these changes occur. Some patients notice significant changes in their forties, whilst others may not observe pronounced differences until later in life. There is no universal timeline, which underscores the importance of individual assessment rather than applying general age-based assumptions to treatment planning.
Is volume loss in the face always related to the fat pads?
Volume loss in the face has multiple contributing factors. Whilst changes in the deep fat pads are a significant component, bone remodelling, collagen and elastin degradation, changes in skin thickness, and alterations in superficial fat compartments all contribute simultaneously. The relative contribution of each factor varies between individuals and may influence which, if any, aesthetic approaches a practitioner recommends. A thorough anatomical assessment is necessary to understand the primary drivers of volume change in any given patient.
Can lifestyle changes reverse deep fat pad volume loss?
Lifestyle measures — including sun protection, a nutritious diet, hydration, and avoiding smoking — can help to slow certain aspects of the ageing process and support overall skin quality. However, they cannot reverse the structural volume loss that occurs within the deep facial fat compartments, as this is driven by metabolic, hormonal, and anatomical processes that are not directly reversible through lifestyle modification alone. Lifestyle and skincare habits are best understood as supportive measures that complement — rather than replace — professional aesthetic assessment for patients with significant volume concerns.
Are dermal fillers the only option for addressing facial volume loss?
Dermal fillers are one of the most commonly discussed non-surgical options for addressing facial volume loss, but they are not the only approach. Depending on individual anatomy, concerns, and the extent of change, a practitioner may discuss a range of options including polynucleotide treatments for tissue quality, skin boosters for hydration and texture, or — for more advanced cases — referral to a surgeon for discussion of surgical approaches such as fat transfer or lifting procedures. Each option carries its own profile of benefits, risks, and limitations, and suitability must be assessed individually.
How do I know if I am a suitable candidate for volume-restoring treatment?
Suitability for any aesthetic treatment depends on a thorough individual assessment by a qualified practitioner. Factors considered typically include overall health, medical history, medications, skin quality, the nature and extent of anatomical changes, and the patient's own goals and expectations. There is no universal eligibility criterion. A professional consultation — which carries no obligation to proceed with any treatment — is the appropriate way to determine whether and which options may be suitable for an individual.
How long do the results of treatments addressing volume loss typically last?
The longevity of results varies depending on the treatment used, the area treated, the product selected, individual metabolism, and lifestyle factors. Hyaluronic acid-based dermal fillers typically last anywhere from 9 to 18 months in most areas, though this varies considerably. No non-surgical treatment produces permanent results. Practitioners will typically discuss expected longevity, maintenance schedules, and what to expect over time during the consultation process. Patients should approach any treatment with the understanding that repeat sessions will be needed to maintain results.
Written by Dr. Shilan Mirian
Lead Aesthetic Practitioner, Pantaleo
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